This study in the British Medical Journal analyzes who is at highest risk of death even after having been vaccinated
The authors of this article use a risk prediction model to stratify risk of severe covid-19 outcomes among people that are already fully vaccinated. They found that the dominant risk factors for breakthrough hospitalization and death are people with:
- Down syndrome
- Kidney transplantation
- Sickle cell disease
- Nursing home residents
- People undergoing chemotherapy
- People with a recent bone marrow or solid organ transplant
- People with HIV/AIDS, dementia, Parkinson’s disease, neurological conditions, and liver cirrhosis.
Everybody in all of these categories should get a booster shot 6 months after they were fully vaccinated.