We usually get our COVID and influenza vaccines right before Halloween. Since AZ often has a later than normal (in the US) flu season I figure waiting until late October might help keep our protection stronger if we have a February flu peak like we often do.
This year, we our COVID vaccine earlier because the virus was running through my parents’ care facility. My mom caught it and spent a week in the hospital.
Then I started seeing early signals that influenza was picking up in the western US, so we moved our flu shots up to this weekend.
An October 7 NPR report describes early increases in flu activity in CA, WA, Hawaii and Alaska. The CDC’s October 2 report describes national flu activity as low but increasing. Here in AZ Pima County reported 27 confirmed flu cases for the week ending September 19, up from 18 the previous week.
Nothing yet suggests that we’re going to have an early Arizona flu season, but the regional signals were enough for me to stop waiting until Halloween.
This year I chose Moderna’s new mRNA influenza vaccine, mFlusiva. A large clinical trial found about 27% fewer laboratory-confirmed symptomatic flu illnesses compared with a standard-dose shot.
I also wanted to share my experience with our members. I’ve been comfortable with the mRNA COVID vaccines, so I was interested in trying this new way.
I’m 66. mFlusiva is FDA-approved for adults 50+ with accelerated approval for those 65+. I could also have chosen an enhanced senior vaccine. The trial result doesn’t show that mFlusiva prevents more illness than those enhanced options.
I got it just a few hours ago so I can’t really tell you much about my experience yet.
You can follow local activity through Pima County’s respiratory reporting website and Maricopa County’s respiratory surveillance dashboard.
Which flu vaccine can you get?
- Fluarix (GSK), FluLaval (GSK) and regular Fluzone (Sanofi): Standard-dose shots made using chicken eggs, licensed for ages 6 months and older.
- Flucelvax (CSL Seqirus): A standard-dose shot made using cell culture rather than eggs, licensed for ages 6 months and older.
- Flublok (Sanofi): An egg-free recombinant protein shot, made using insect cell culture, licensed for ages 9 and older.
- Fluzone High-Dose (Sanofi): A shot made using chicken eggs, having four times the antigen of a standard-dose shot, licensed for adults 65 and older.
- Fluad (CSL Seqirus): A shot made using chicken eggs, with an added ingredient that strengthens the immune response, licensed for adults 65 and older.
- FluMist (AstraZeneca): A nasal spray made using chicken eggs, having weakened live influenza viruses, licensed for ages 2–49. It isn’t appropriate during pregnancy or for people with certain medical conditions.
- mFlusiva (Moderna): An egg-free mRNA shot, manufactured without growing influenza viruses in eggs or cell culture, licensed for adults 50 and older, with accelerated approval for those 65 and older.
For adults 65+, CDC preferentially recommends high-dose, adjuvanted or recombinant vaccines. The American Academy of Family Physicians also includes mRNA among its preferred options.








